Cannabidiol (CBD) and tetrahydrocannabinol (THC) are both cannabinoids that are found in the cannabis plant (hemp or marijuana).
The main difference between CBD and THC is that, unlike THC, CBD does not have psychoactive properties and does not cause a high. CBD alone is primarily used for medicinal purposes and does not have the potential to cause addiction or substance abuse.
What is CBD?
Cannabidiol (CBD) is one of the hundreds of cannabinoids present in the cannabis plant. It is used in a broad range of products:
- Oral: Available in the form of over-the-counter tablets and capsules
- Oil and tinctures: Contain a high concentration of CBD
- Topicals: Can be applied directly to the skin, hair, or nails
- Vape liquids: Found in certain e-cigarette liquids, which are vaporized in the same way as other vape liquids
- Foods and drinks: Several brands have started to incorporate CBD into various foods and beverages such as chocolate and coffee
What is THC?
Tetrahydrocannabinol (THC) is the predominant psychoactive ingredient found in the cannabis plant. THC is found in marijuana and used as an ingredient in capsules, edibles, and oils.
According to the National Institute on Drug Abuse (NIDA), THC works by activating the brain by signaling the release of the brain chemical dopamine. Dopamine is a neurotransmitter that plays a crucial role in mood and pleasure. THC triggers a higher-than-normal release of dopamine, leading to feelings of euphoria.
CBD vs. THC
CBD and THC interact with the body in a variety of ways, one of which is by mimicking and augmenting the effects of the compounds in the body called endogenous cannabinoids, a part of the endocannabinoid system (which maintains homeostasis).
| Differences | CBD | THC |
|---|---|---|
| Source |
|
|
| Psychoactive or addictive properties | Not present | Present |
| Ability to produce a high | No | Yes |
| Used for medicinal purposes | Yes | No |
| Potential health benefits |
|
|
| Pain relief | Yes | Yes |
| Legality | Certain forms of CBD are legal in most states | Some states allow the recreational use of marijuana and THC-containing products |
| Covered under the U.S. Controlled Substances Act | Yes | Yes |
SLIDESHOW
16 Foods That Boost and Improve Your Immune System See SlideshowWhat are the potential side effects of CBD vs. THC?
Cannabidiol (CBD) side effects
CBD may produce side effects such as:
- Nausea
- Irritability
- Gastrointestinal upset (reduced appetite or diarrhea)
- Fatigue
- Liver injury
- Drowsiness
- Agitation
- Mood changes
Some studies have reported that CBD can interact with blood thinners such as warfarin and may increase the risk of bleeding. Animal studies have reported that CBD consumption during pregnancy may damage the reproductive organs in male fetuses.
Avoid using CBD while taking the following medications:
- Antibiotics
- Anticancer medications
- Blood pressure medications
- Cholesterol medications
- Antihistamines
- Antimicrobials
- Heart rhythm medications
- Immune modulators
- Antipsychotics and antidepressants
Tetrahydrocannabinol (THC) side effects
THC can have several short-term and long-term adverse effects, including:
- Impaired short-term memory
- Altered judgment
- Impaired coordination
- Cognitive impairment
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Health Solutions From Our Sponsors
Health Benefits of CBD. https://www.webmd.com/diet/health-benefits-cbd#1
What Is CBD? https://www.projectcbd.org/about/what-cbd
Evidence for THC versus CBD in cannabinoids. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042662/
Cannabis (Marijuana) and Cannabinoids: What You Need To Know. https://www.nccih.nih.gov/health/cannabis-marijuana-and-cannabinoids-what-you-need-to-know
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